THeTA2 estimates tumour purity and clonal / subclonal copy number.
THeTA2 (Tumor Heterogeneity Analysis) is an algorithm that estimates the tumour purity and clonal / subclonal copy number aberrations directly from high-throughput DNA sequencing data.
The THeTA2 MultiQC module plots the % germline and % tumour subclone for each sample.
Note that each sample can have multiple maximum likelihood solutions - the MultiQC
module plots proportions for the first one in the results file (
Also note that if there are more than 5 tumour subclones, their percentages are summed.
File search patterns
theta2: fn: "*.BEST.results"